SN-38

• Product NameSN-38
  CAS No.86639-52-3
  Purity>98%
  Min Quantity
  Price~
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  Molecular Structure

Detailed Description

SN-38SN-38(NK-012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks.

IC50 Value:

Target: topoisomerase I

in vitro: Among TIs, SN-38 had the highest cytotoxicity towards OSCC cell lines, with a tumor specificity index of 1321 compared to mesenchymal cells and 22 compared with epithelial cells.

Target:Glucocorticoid Receptor

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