EPZ-6438

• Product NameEPZ-6438
  CAS No.1403254-99-8
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

EPZ-6438EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5±0.5 nM.

IC50 Value: 2.5±0.5 nM (PRC2-containing wild-type EZH2) [1]

Target: EZH2; HMTase

in vitro: EPZ-6438 inhibited the activity of human PRC2-containing wild-type EZH2 with an inhibition constant (Ki) value of 2.5 ± 0.5 nM, and similar potency was observed for EZH2 proteins bearing all known lymphoma change-of-function mutations.

Target:Others

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