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ICG-001

    Detailed Description

    ICG-001CG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.

    IC50 value: 3 uM

    Target: Wnt

    in vitro: ICG-001 has no effect on the related reporter construct, FOPFLASH, which contains mutated TCF sites.

    Target:Monoamine Oxidase

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