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VE-822

    Detailed Description

    VE-822VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM).

    IC50 Value: 0.2 nM (Ki); 19 nM (Cell IC50) [1]

    Target: ATR

    in vitro: VE-822, a close analog of VE-821, has increased potency against ATR retaining the excellent ATR selectivity pro?le.

    Target:DNA alkylator_crosslinker

    Product Links:http://www.medchemexpress.cn/ve-822.html

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