Talarozole

• Product NameTalarozole
  CAS No.201410-53-9
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

TalarozoleTalarozole(R115866) is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid for the treatment of psoriasis and acne.

IC50 Value:

Target: CYP26

in vitro: Talarozole treatment increased the mRNA expression of CRABP2, KRT4, CYP26A1 and CYP26B1 dose dependently, and decreased theexpression of KRT2 and IL-1alpha compared with vehicle-treated skin.

Target:/products

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