GSK126

• Product NameGSK126
  CAS No.1346574-57-9
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

GSK126GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase with Ki value of 0.5 nM.

IC50 Value: 0.5 nM (Ki)

Target: EZH2

in vitro: Although GSK126 induced loss of H3K27me3 independent of EZH2 mutation status, six of seven lymphoma cell lines sensitive to GSK126 treatment were EZH2-mutation(+), while only two of 11 lymphoma cell lines less sensitive to GSK126 were EZH2-mutation(+) [1].

Target:FGFR

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