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Bortezomib

  • CAS No:179324-69-7 [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]<br />amino]butyl]boronic acid
    Molecular Structure

    Detailed Description

    BortezomibBortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM.

    IC50 value: 0.6 nM (Ki) [1]

    Target: 20S proteasome

    in vitro: The average growth inhibition of 50% value for Bortezomib across the entire panel of 60 cancer cell lines derived from multiple human tumors from the US National Cancer Institute (NCI) is 7 nM.

    Target:HDAC

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