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  • Street: 18 Wilkinson Way, Princeton, NJ 08540, USA
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SU5416

    Detailed Description

    SU5416Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR.

    IC50 value: 1.23 uM [1]

    Target: VEGFR

    in vitro: Semaxanib inhibits VEGF-dependent phosphorylation of the Flk-1 receptor in Flk-1-overexpressing NIH 3T3 cells with IC50 of 1.04 μM.

    Target:Antibacterial

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