MK 2206
Detailed Description
MK 2206MK-2206 2Hcl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively; no inhibitory activities against 250 other protein kinases observed.
IC50 value: 8 nM/12 nM/65 nM(Akt1/2/3) [1]
Target: Akt1/2/3
in vitro: MK-2206 is an allosteric inhibitor and is activated by the pleckstrin homology domain.
Target:Akt
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