Dasatinib

• Product NameDasatinib
  CAS No.302962-49-8
  Purity>98%
  Min Quantity
  Price~
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  Molecular Structure

Detailed Description

DasatinibDasatinib(BMS-354825) is a potent and dual Abl/ Src inhibitor IC50 of <1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM.

IC50 value: <1 nM/0.8 nM(Abl/ Src); 79 nM/37 nM (c-Kit WT/c-Kit D816V) [1] [2]

Target: Abl; Src; c-Kit

in vitro: Dasatinib is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I.

Target:Aurora Kinase

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