Cediranib

• Product NameCediranib
  CAS No.288383-20-0
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

CediranibCediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3.

IC50 value: 0.5 nM (VEGFR2); 5 nM/≤3 nM(Flt1/4) [1]

Target: VEGFR2; Flt1/4

in vitro: Cediranib inhibits VEGF-stimulated proliferation with IC50 of 0.4 nM.

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