SCH 527123SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.
IC50 value: 42 nM (CXCR1); 3 nM (CXCR2) [1]
Target: CXCR1/2
in vitro: Sch527123 inhibits chemokine binding to CXCR1 and CXCR2 receptors in an insurmountable manner and is categorized as an allosteric antagonist.