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SCH527123

    Detailed Description

    SCH 527123SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.

    IC50 value: 42 nM (CXCR1); 3 nM (CXCR2) [1]

    Target: CXCR1/2

    in vitro: Sch527123 inhibits chemokine binding to CXCR1 and CXCR2 receptors in an insurmountable manner and is categorized as an allosteric antagonist.

    Target:Survivin

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