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Olaparib

  • CAS No:763113-22-0 4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]<br />methyl]-2H-phthalazin-1-one
    Molecular Structure

    Detailed Description

    OlaparibOlaparib (AZD2281, KU0059436) is a potent PARP inhibitor with IC50 of 5 and 1 nM for PARP-1and PARP-2, respectively.

    IC50 Value: 5 nM(PARP-1); 1 nM(PARP-2)

    Target: PARP

    in vitro: Olaparib would act against BRCA1 or BRCA2 mutations.

    Target:PARP

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