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  • Street: 18 Wilkinson Way, Princeton, NJ 08540, USA
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LCL161

    Detailed Description

    LCL161LCL161 is an orally bioavailable SMAC mimetic and inhibitor of Inhibitor of Apoptosis Protein (IAP) family of proteins, with antineoplastic activity.

    IC50 Value:

    Target: IAP

    in vitro: Huh-7 cells co-treated with LCL161 and SC-2001 showed a significant dose-dependent apoptotic effect demonstrated by sub-G1 assay and cleavage of PARP.

    Target:CFTR

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