CC-930
Detailed Description
CC-930CC-930(Tanzisertib) is a selective and potent JNK1/JNK2/JNK3(IC50=61/7/6 nM) inhibitor and is currently under clinical development for fibrotic and infammatory indications.
IC50 Value: 61 nM (JNK1); 7 nM (JNK2); 6 nM (JNK3) [1]
Target: JNK1/2/3
in vitro: Compound 1 (CC-930) showed remarkable selectivity in a panel of 240 kinases, EGFR being the only non-MAP kinase inhibited more than 50% at 3 lM (IC50 = 0.38 lM).
Target:/products
Product Links:http://www.medchemexpress.cn/cc-930.html
Permanent link:http://www.medchemexpress.com/cc-930.html