SEA0400

• Product NameSEA0400
  CAS No.223104-29-8
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

SEA0400SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).

IC50 value: 5-33 nM

Target: NCX

SEA0400, a specific Na+/Ca2+ exchange (NCX) inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease and attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.

Target:HIV

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