Home > Name List By other > (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11, 17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15, 16-octahydro-...

CAS No 53-34-9 , (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,
16-octahydro-6H-cyclopenta[a]phenanthren-3-one

  • Name: (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,
    16-octahydro-6H-cyclopenta[a]phenanthren-3-one
  • Synonyms: Prednisolone;Alphadrol; 6alpha-fluoro-; 6alpha-Fluoroprednisolone; Vladicort;(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,
    16-octahydro-6H-cyclopenta[a]phenanthren-3-one; 53-34-9; Etadrol; Fluprednisolonum [INN-Latin]; Isopredon;
  • CAS Registry Number:
  • Melting Point: 208 - 213
  • Density: 1.35 g/cm3
  • Refractive index: 1.597
  • EINECS: 200-170-8
  • Molecular Weight: 378.434483
  • InchiKey: MYYIMZRZXIQBGI-HVIRSNARSA-N
  • InChI: InChI=1S/C21H27FO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,
    17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7,12-13,15-16,18,23,25,27H,4,
    6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1
  • Molecular Formula: C21H27FO5
  • Molecular Structure:CAS No:53-34-9 (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,<br />17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,<br />16-octahydro-6H-cyclopenta[a]phenanthren-3-one

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References of (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,
16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Title: Fluprednisolone
CAS Registry Number: 53-34-9
CAS Name: (6a,11b)-6-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
Synonyms: 6a-fluoroprednisolone; 6a-fluoro-1,4-pregnadiene-11b,17a,21-triol-3,20-dione; 6a-fluoro-1-dehydrohydrocortisone
Manufacturers' Codes: U-7800; NSC-47439
Trademarks: Etadrol (Farmitalia)
Molecular Formula: C21H27FO5
Molecular Weight: 378.43
Percent Composition: C 66.65%, H 7.19%, F 5.02%, O 21.14%
Literature References: Prepn: Hogg, Spero, US 2841600 (1958 to Upjohn); Batres et al., DE 1079042 (1960 to Syntex); Lettré, Hotz, DE 1088953 (1960 to Bayer).
Properties: Crystals, mp 208-213°. [a]D +92°.
Melting point: mp 208-213°
Optical Rotation: [a]D +92°
 
Derivative Type: 21-Acetate
Molecular Formula: C23H29FO6
Molecular Weight: 420.47
Percent Composition: C 65.70%, H 6.95%, F 4.52%, O 22.83%
Properties: Crystals, mp 235-238°.
Melting point: mp 235-238°
 
Therap-Cat: Glucocorticoid; anti-inflammatory.
Therap-Cat-Vet: Anti-inflammatory.
Keywords: Glucocorticoid.