Home > Name List By other > (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11, 17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15, 16-octah...

CAS No 4419-39-0 , (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
16-octahydrocyclopenta[a]phenanthren-3-one

  • Name: (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthren-3-one
  • Synonyms: Becloval; Becodisks; Inalone; Beconasol;Beclometasone; Beclometasonum; Anceron; Beclometasona; Becotide;(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
    16-octahydrocyclopenta[a]phenanthren-3-one;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 210 C
  • Flash Point: 316.8°C
  • Boiling Point: 600.2°C at 760 mmHg
  • Density: 1.35g/cm3
  • Refractive index: 1.61
  • Water Solubility: Slightly soluble
  • Hazard Symbols: UN NO.
  • Flash Point: 316.8°C
  • EINECS: 224-585-9, 226-886-0
  • Molecular Weight: 408.91566
  • InchiKey: NBMKJKDGKREAPL-DVTGEIKXSA-N
  • InChI: InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,
    23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,
    8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
  • Molecular Formula: C22H29ClO5
  • Molecular Structure:CAS No:4419-39-0 (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,<br />17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,<br />16-octahydrocyclopenta[a]phenanthren-3-one

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4419-39-0 BECLOMETHASONE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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4419-39-0 Beclomethasone

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4419-39-0 Beclomethasone

  • United States LGM Pharma [Manufacturer]
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4419-39-0 Beclomethasone

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4419-39-0 Beclomethasone

  • Beclomethasone9-alpha-Chloro-16-beta-methylprednisolone
  • Canada Toronto Research Chemicals [Manufacturers]
  • Tel: (416) 665-9696, 800-727-9240
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4419-39-0 BECLOMETHASONE-D3

  • India VARDA Biotech (P) Ltd. [Manufacturer]
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4419-39-0 Pregna-1,4-diene-3,20-dione,9-chloro-11,17,21-trihydroxy-16-methyl-, (11b,16b)-

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4419-39-0 Pregna-1,4-diene-3,20-dione,9-chloro-11,17,21-trihydroxy-16-methyl-, (11b,16b)-

  • United Kingdom Andard-Mount Company Ltd. [Manufacturers]
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4419-39-0 1,4-PREGNADIEN-9ALPHA-CHLORO-16BETA-METHYL-11BETA,17ALPHA, 21-TRIOL-3, 20-DIONE

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References of (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,
16-octahydrocyclopenta[a]phenanthren-3-one
Title: Beclomethasone
CAS Registry Number: 4419-39-0
CAS Name: (11b,16b)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Synonyms: 9a-chloro-16b-methyl-1,4-pregnadiene-11b,17a,21-triol-3,20-dione; 9a-chloro-16b-methylprednisolone
Molecular Formula: C22H29ClO5
Molecular Weight: 408.92
Percent Composition: C 64.62%, H 7.15%, Cl 8.67%, O 19.56%
Literature References: Glucocorticoid. Prepn of free alcohol and 21-acetate: GB 912378 (1962 to Merck & Co.); of 21-acetate: GB 901093 (1962 to Schevico); of mono and diesters: J. Elks et al., BE 649170; eidem, US 3312590 (1964, 1967 both to Glaxo). Symposium on clinical studies: Br. J. Clin. Pharmacol. 4, Suppl. 3, 249S-312S (1977). Use in chronic asthma in children: M. Rao et al., J. Asthma 19, 21 (1982); in treatment of asthma in steroid-independent adults: V. A. Malfitan, Clin. Ther. 4, 472 (1982). Review of use in rhinitis: P. Small et al., Ann. Allergy 49, 127 (1982); of pharmacology, side effects and use in asthma and allergic rhinitis: R. N. Brogden et al., Drugs 28, 99-126 (1984).
 
Derivative Type: Dipropionate
CAS Registry Number: 5534-09-8
Manufacturers' Codes: Sch-18020W
Trademarks: Aerobec (3M Pharma); Aldecin (Schering-Plough); Anceron (Schering-Plough); Andion (GEA); Beclacin (Kaigai); Becloforte (GSK); Beclomet (Orion); Beclorhinol (Lindopharm); Beclovent (GSK); Becodisks (GSK); Beconase (GSK); Beconasol (GSK); Becotide (GSK); Clenil-A (Chiesi); Entyderma (Taiyo); Inalone (Lampugnani); Korbutone (Nippon Glaxo); Propaderm (GSK); Qvar (3M); Rino-Clenil (Chiesi); Sanasthmax (GSK); Vancenase (Schering-Plough); Vanceril (Schering-Plough); Viarex (Schering-Plough); Viarox (Byk Gulden)
Molecular Formula: C28H37ClO7
Molecular Weight: 521.04
Percent Composition: C 64.54%, H 7.16%, Cl 6.80%, O 21.49%
Properties: Crystals from acetone + ether, mp 117-120° (dec). [a]D +98.0° (c = 1.0 in dioxane). uv max (ethanol): 238 nm (e 15990).
Melting point: mp 117-120° (dec)
Optical Rotation: [a]D +98.0° (c = 1.0 in dioxane)
Absorption maximum: uv max (ethanol): 238 nm (e 15990)
 
Therap-Cat: Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).
Keywords: Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant); Glucocorticoid.