Home > Name List By other > (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11, 17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15, 16-hexahydro-8H-cycl...

CAS No 5251-34-3 , (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,
16-hexahydro-8H-cyclopenta[a]phenanthren-3-one

  • Name: (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,
    16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
  • Synonyms: Cloprednole;Cloradryn; Novacort; RS-4691; Cloprednolum; RS 4691; Synestan; Syntestan;(8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,
    17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,
    16-hexahydro-8H-cyclopenta[a]phenanthren-3-one; 5251-34-3;
  • CAS Registry Number:
  • Flash Point: 316.9°C
  • Boiling Point: 600.3°Cat760mmHg
  • Density: 1.4g/cm3
  • Refractive index: 1.635
  • Flash Point: 316.9°C
  • EINECS: 226-052-6
  • Molecular Weight: 392.8732
  • InchiKey: YTJIBEDMAQUYSZ-FDNPDPBUSA-N
  • InChI: InChI=1S/C21H25ClO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,
    17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7-8,12-13,16,18,23,25,27H,4,6,
    9-10H2,1-2H3/t12-,13-,16-,18+,19-,20-,21-/m0/s1
  • Molecular Formula: C21H25ClO5
  • Molecular Structure:CAS No:5251-34-3 (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,<br />17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,<br />16-hexahydro-8H-cyclopenta[a]phenanthren-3-one

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5251-34-3 CLOPREDNOL

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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5251-34-3 Chloroprednisone

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5251-34-3 Cloprednol

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5251-34-3 Chloroprednisone

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5251-34-3 Pregna-1,4,6-triene-3,20-dione,6-chloro-11,17,21-trihydroxy-, (11b)-

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References of (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,
17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,
16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
Title: Cloprednol
CAS Registry Number: 5251-34-3
CAS Name: (11b)-6-Chloro-11,17,21-trihydroxypregna-1,4,6-triene-3,20-dione
Synonyms: 6-chloro-D1,4,6-pregnatriene-11b,17a,21-triol-3,20-dione
Manufacturers' Codes: RS-4691
Trademarks: Cloradryn (Recordati); Novacort (Syntex); Syntestan (Syntex)
Molecular Formula: C21H25ClO5
Molecular Weight: 392.87
Percent Composition: C 64.20%, H 6.41%, Cl 9.02%, O 20.36%
Literature References: Prepn: H. J. Ringold, G. Rosenkranz, FR 1271981 C.A. 58, 1148a (1963); eidem, US 3232965 (1962, 1966 both to Syntex). Metabolic effects: E. Ortega et al., J. Clin. Pharmacol. 16, 122 (1976). Effects on hypothalamic-pituitary-adrenal axis function: eidem, J. Int. Med. Res. 4, 326 (1976). Bioavailability in humans: E. Mroszczak et al., J. Pharm. Sci. 67, 920 (1978). HPLC determn in plasma: C. Lee et al., ibid. 70, 669 (1981).
Properties: Crystals from acetone/hexane.
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.