Home > Name List By 4 > 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid

CAS No 153559-49-0 , 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
acid

  • Name: 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
    acid
  • Synonyms: 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
    acid;Targretin; Targret; Targrexin; LGD1069; Targretin-gel; Targretyn; 153559-49-0; bexaroteno; LGD 1069;
  • CAS Registry Number:
  • Density: 1.042
  • Molecular Weight: 348.47792
  • InchiKey: NAVMQTYZDKMPEU-UHFFFAOYSA-N
  • InChI: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,
    3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,
    3-6H3,(H,25,26)
  • Molecular Formula: C24H28O2
  • Molecular Structure:CAS No:153559-49-0 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic<br />acid
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153559-49-0 Bexarotene

  • Catalog No.: FT-0657110 CAS No.: 153559-49-0 NAME: Bexarotene Synonyms: 3-methyl-TTNEB IUPAC Name: 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid InChI: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(...
  • China Finetech Industry Limited [Manufacturer]
  • Tel: 86-027-87465837
  • Address: Chukang Road,Wuhan, P.R.China (China Office) wuhan,HubeiChina
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153559-49-0 Bexarotene

  • Bexarotene
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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153559-49-0 BEXAROTENE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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153559-49-0 Bexarotene

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
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153559-49-0 Bexarotene

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153559-49-0 Bexarotene

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
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153559-49-0 bexarotene

  • chemrenblock supply bexarotene/cas:153559-49-0 chemrenblock will assure you the best price you can get in the market. If the demand in this area, please contact us www.chemrenblock.com
  • China Chemenblock Bio-Enginee ing Co., Ltd [Manufacturer]
  • Tel: 86-0519-85788828
  • Fax: 86-0519-89960117
  • Address: No.254 Qintan Road changzhou,JiangsuChina
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153559-49-0 BEXAROTENE

  • China Hainan Zhongxin Chemical Co., Ltd. [Manufacturer]
  • Tel: + 86 898 6854 0310/ + 86 21 64361616
  • Fax: + 86 898 6854 0119
  • Address: HAINAN COMPANY
    Address: Rm 811, Hainan Mandarin Hotel,
    Binhai Avenue, Haikou city,
    Hainan, P.R.China
    Tel: + 86 898 6854 0310
    Fax: + 86 898 6854 0119 ,China
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153559-49-0 BEXAROTENE

  • BEXAROTENE
  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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153559-49-0 Bexarotene

  • China Hangzhou Sage Chemical Co., Ltd. [, Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, ,ZhejiangChina
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References of 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
acid
Title: Bexarotene
CAS Registry Number: 153559-49-0
CAS Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Manufacturers' Codes: SR-11247; LGD-1069
Trademarks: Targretin (Ligand)
Molecular Formula: C24H28O2
Molecular Weight: 348.48
Percent Composition: C 82.72%, H 8.10%, O 9.18%
Literature References: Selective retinoid X receptor (RXR) agonist. Prepn: M. F. Boehm et al., WO 9321146 (1993 to Ligand Pharm.); M. L. Dawson et al., US 5466861 (1995 to SRI Int.; La Jolla Cancer Res. Found.); and structure-activity study: M. F. Boehm et al., J. Med. Chem. 37, 2930 (1994); M. I. Dawson et al., ibid. 38, 3368 (1995). Chemopreventive effect in rat mammary carcinoma: M. M. Gottardis et al., Cancer Res. 56, 5566 (1996). Effect on glucose homeostasis in exptl diabetes: R. Mukherjee et al., Nature 386, 407 (1997). Clinical pharmacokinetics and evaluation in advanced cancers: V. A. Miller et al., J. Clin. Oncol. 15, 790 (1997). Clinical evaluation in cutaneous T-cell lymphoma: D. Breneman et al., Arch. Dermatol. 138, 325 (2002).
Properties: White solid from methylene chloride, mp 230-231° (Dawson, 1995); also reported as white crystals, mp 234° (Boehm, 1994). uv max (methanol): 264 nm (e 16400).
Melting point: mp 230-231° (Dawson, 1995); mp 234° (Boehm, 1994)
Absorption maximum: uv max (methanol): 264 nm (e 16400)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Retinoids and Analogs.