Home > Name List By 4 > 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid

CAS No 153559-49-0 , 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
acid

  • Name: 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
    acid
  • Synonyms: 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
    acid;Targretin; Targret; Targrexin; LGD1069; Targretin-gel; Targretyn; 153559-49-0; bexaroteno; LGD 1069;
  • CAS Registry Number:
  • Density: 1.042
  • Molecular Weight: 348.47792
  • InchiKey: NAVMQTYZDKMPEU-UHFFFAOYSA-N
  • InChI: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,
    3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,
    3-6H3,(H,25,26)
  • Molecular Formula: C24H28O2
  • Molecular Structure:CAS No:153559-49-0 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic<br />acid
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153559-49-0 Bexarotene

  • Bexarotene, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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153559-49-0 BEXAROTENE

  • United States Carbomer, Inc. [Manufacturer]
  • Tel: 858-552-0992/ (800) 239-7129
  • Fax: 858-552-0999
  • Address: PO Box 261026-1026
    San Diego, CA 92196 null,nullUnited States
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153559-49-0 Bexarotene

  • China Wuxi Mizat Chemical Technology Co., Ltd. [Manufacturer]
  • Tel: +86-510-86106900/ +86-510-86125752
  • Fax: +86-510-86125752
  • Address: No.205,zhencheng Road,
    HI-TECT District,
    Wuxi, Jiangsu,China null,nullChina
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153559-49-0 bexarotene

  • Spot sales we will assure you the best price you can get in the market. If the demand in this area, please contact us www.chemrenpharm.com Contact: chemrenpharm@sina.com 117.1029712-80-8 INCB28060 118.927880-90-8 RAF265(CHIR-265) 119.648450-29-7 AS-6...
  • China Chemren Bio-Engineering Co., Ltd [Manufacturer]
  • Tel: 86-0519-85788828
  • Address: No.254 Qintan Road Changzhou, Jiangsu,PRC changzhou,JiangsuChina
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153559-49-0 Bexarotene

  • China Haihang Industry Co., Ltd. null
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, null,nullChina
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153559-49-0 Bexarotene

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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153559-49-0 BEXAROTENE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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153559-49-0 Bexarotene

  • China Laiwu Hehui Chemical Co.,Ltd. null
  • Tel: +86-(531)-88772589
  • Fax: +86-(531)-88772589
  • Address: Huashan Rd., Jinan City, Shandong 250000, null,nullChina
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153559-49-0 1-Bexarotene

  • 1-Bexarotene
  • United States Medical Isotopes, Inc. [Manufacturer]
  • Tel: (603) 635-2255/ (800) 374-9513
  • Fax: (603) 635-2448
  • Address: 100 Bridge Street
    Pelham, NH 03076 null,nullUnited States
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153559-49-0 Bexarotene

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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References of 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
acid
Title: Bexarotene
CAS Registry Number: 153559-49-0
CAS Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Manufacturers' Codes: SR-11247; LGD-1069
Trademarks: Targretin (Ligand)
Molecular Formula: C24H28O2
Molecular Weight: 348.48
Percent Composition: C 82.72%, H 8.10%, O 9.18%
Literature References: Selective retinoid X receptor (RXR) agonist. Prepn: M. F. Boehm et al., WO 9321146 (1993 to Ligand Pharm.); M. L. Dawson et al., US 5466861 (1995 to SRI Int.; La Jolla Cancer Res. Found.); and structure-activity study: M. F. Boehm et al., J. Med. Chem. 37, 2930 (1994); M. I. Dawson et al., ibid. 38, 3368 (1995). Chemopreventive effect in rat mammary carcinoma: M. M. Gottardis et al., Cancer Res. 56, 5566 (1996). Effect on glucose homeostasis in exptl diabetes: R. Mukherjee et al., Nature 386, 407 (1997). Clinical pharmacokinetics and evaluation in advanced cancers: V. A. Miller et al., J. Clin. Oncol. 15, 790 (1997). Clinical evaluation in cutaneous T-cell lymphoma: D. Breneman et al., Arch. Dermatol. 138, 325 (2002).
Properties: White solid from methylene chloride, mp 230-231° (Dawson, 1995); also reported as white crystals, mp 234° (Boehm, 1994). uv max (methanol): 264 nm (e 16400).
Melting point: mp 230-231° (Dawson, 1995); mp 234° (Boehm, 1994)
Absorption maximum: uv max (methanol): 264 nm (e 16400)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Retinoids and Analogs.