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GDC-0152

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:GDC-0152
  • CAS No: 873652-48-3

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GDC-0152GDC-0152 is a potent inhibitor of IAPs; binds to the XIAP BIR3 domain, the BIR domain of ML-IAP, and the BIR3 domains of cIAP1 and cIAP2 with K(i) values of 28, 14, 17, and 43 nM, respectively.

IC50 value: 28/14/17/43 nM(Ki, XIAP/ML-IAP/cIAP1/cIAP2) [1]

Target: IAPs inhibitor

in vitro:GDC-0152 can block protein?protein interactions that involve IAP proteins and pro-apoptotic molecules.

Target:PARP

Product Links:http://www.medchemexpress.cn/gdc-0152.html

Permanent link:http://www.medchemexpress.com/GDC-0152.html

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