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Vismodegib(GDC-0449)

  • Purity: 98%
  • Price: USD 350~1000/Kilograms
  • Place of Orign: wuhan,Hubei,China
Ms.Luna Wang

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Item specifics

  • Product Name.:Vismodegib(GDC-0449)
  • CAS No: 314245-33-5

Details

IU1 is a reversible and specific inhibitor of proteasome-associating Usp14. It does not inhibit other deubiquitinating enzymes of the 26S proteasome. It partially inhibits the ubiquitin chain trimming activity of the 26S proteasome, which could function to stimulate the degradation of some proteasomal substrates.

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