Axitinib
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Molecular Structure
Detailed Description
Axitinib
Synonyms:Axitinib;Benzamide, n-methyl-2-[[3-[(1e)-2-(2-pyridinyl)ethenyl]-1h-indazol-6-yl]thio]-;N-methyl-2-{[3-((e)-2-pyridin-2-ylvinyl)-1h-indazol-6-yl]sulfanyl}benzamide;N-methyl-2-((3-((1e)-2-(pyridin-2-yl)ethenyl)-1h-indazol-6-yl)sulfanyl)benzamide;Avermectinb;Axitinib for research;Ag 013736;N-methyl-2-[[3-[(1e)-2-(2-pyridinyl)ethenyl]-1h-indazol-6-yl]thio]benzamide
CAS:319460-85-0
MF:C22H18N4OS
MW:386.47
Product Categories:Inhibitors;Pharmaceuticals;Protein Kinase Inhibitors and Activators
Chemical Properties:Off-White Solid
Assay:99%
Usage:A tyrosine kinase inhibitor; used in cancer therapy. Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.
Packing:1kg /foli bag
- Axitinib