Pirfenidone
-
Molecular Structure
Detailed Description
Pirfenidone
Synonyms:5-methyl-1-phenyl-2(1h)-pyridon;Amr-69;Pirfenidone;5-methyl-1-phenyl-1h-pyridin-2-one;5-methyl-1-phenyl-2(1h)-pyridinone;5-methyl-1-phenyl-2-(1h)-pyridone;5-methyl-n-phenyl-2-1h-pyridone;Pirfenidone also see 5-methyl-1-phenyl-2(1h)-pyridinone
Cas:53179-13-8
Mf:C12h11no
Mw:185.22
Product categories:Aromatics compounds;Aromatics;Heterocycles;Intermediates & fine chemicals;Pharmaceuticals;Cytokine signaling
Chemical properties:Off-white solid
Usage:Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver
Biological activity:Antifibrotic agent, effective in models of pulmonary and lung fibrosis.Inhibits collagen production and fibroblast proliferation.Regulates cytokine levels following oral administration in vivo .Potent scavenger of free radicals and inhibitor of lipid peroxidation.
Packing:1kg/foil bag or as required
Item Standard
Appearance White crystal powder
Melting Point 102--109??
Loss on drying <1.0%
Known single impurity <1.0%
Unknown single impurity <0.5%
Total impurity <2.0%
Assay(as dried) 99%
- Pirfenidone