Griseofulvin

• Product NameGriseofulvin
  CAS No.126-07-8
  Purity99%
  Min Quantity1000Kilograms
  Price1~2
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  Molecular Structure

Detailed Description

(+)-Griseofulvin
Synonyms:(+)-griseofulvin;griseofulvin;[2s-trans]-7-chloro-2,4,6-trimethoxy-6'-methylspiro[benzofuran-2(3h), 1'(2)-cyclohexane]-3,4'-dione;(2s)-trans-7-chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3h],1'-[2]cyclohexene)-3,4'-dione;7-chloro-2',4,6-trimethoxy-6'-methyl-, (1's-trans)-spiro(benzofuran-2(3h),1'-(2)cyclohexene)-3,4'-dione;(+)-griseofulvi;(2s-trans)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3h),1’-[2]cy;(2s-trans)-xy-6’-methyl
CAS:126-07-8
MF:C17H17ClO6a
MW:352.77
EINECS:204-767-4
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Antifungal;Aromatics;Chiral Reagents
Chemical Properties:Crystalline Solid
Usage:adrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic.antifungal, inhibits mitosis in metaphase.
Packing:25kg/drum

Test ItemsSpecificationTest Results
CharacteristicsA yellowish-white,microfine powderyellowish-white,microfine powder
Melting point220oC About 220oC218.4oC-219.4oC
Specific optical rotation+354o~+364o+356o
IdentificationMeets the requirementsMeets the requirements
Check-up Particles sizeMeets the requirementsMeets the requirements
Acidity0.25g consumed 0.02mol/l NaOH not more intensely coloured than reference solution Y40.6ml
Clarity and colour of solutionThe solution is clear and not more intensely coloured than reference solution Y4Y5~Y6 Clear Y5~Y6
Matter soluble in petroleum spirit?ü0.2%0.1%
Sulphated ash≤0.2%0.1%
Related substances-Cl:<0.60 -H<0.15-Cl:0.48-H:0.04
Loss on drying ≤1.0%0.1%
Abnormal toxicityMeets the requirementsMeets the requirements
assay(on the anhydrous substance)97.0%~102.0%98.3%
ConclusionThe above certificate of analysis is in compliance with BP/EP,meets the standard requirements.
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• Griseofulvin