Indometacin
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Molecular Structure
Detailed Description
Indometacin
Synonyms:Aurora ka-6542;Indocin;Indometacin;Indometacine;Indomethacin;Indomethacine;Labotest-bb lt00244830;1-(p-chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid
Cas:53-86-1
Mf:C19h16clno4
Mw:357.79
Einecs:200-186-5
Product categories:Pharmaceuticals;Active pharmaceutical ingredients;Inhibitors;Intermediates & fine chemicals;Lipid signaling
Chemical properties:Crystalline solid
Assay:99%
Usage:Antiinflammatory, antipyretic, analgesic.Inhibits cyclooxygenase (ic50=0.1um) selectively over liposygenases (ic50=100um for 5-,12- and 15-lo).A clinically useful naisd.
Air & water reactions practically insoluble in water.Decomposes in alkali.
Reactivity profile a weak organic acid.
Packing:25kg/drum or as required
ITEMS SPECIFICATIONS RESULTS
Characteristics White or yellow crystalline powder Yellow crystalline powder
Identification
A:Melting point 158~162160.0~162.0
C:Infrared Absorpt on spectrum Meets the requirements Meets the requirements
Tests
Related substances Meets the requirementsMeets the requirements
Heavy metals ≤20ppm <20ppm
Loss on drying ≤0.5% 0.05%
Sulphated ash ≤0.1% 0.05%
Assay 98.5%~100.5% 99.59%
Particle Size 80%particle less than 80um Meets the requirements
Conclusion The above product conforms to BP2009
- Indometacin