ST 2825ST 2825 is a MyD88 pharmacologic inhibitor.
IC50 value:
Target: MyD88
ST2825 inhibited MyD88 dimerization in coimmunoprecipitation experiments.ST2825 interfered with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1beta-mediated activation of NF-kappaB transcriptional activity.