AMG 232

• Product NameAMG 232
  CAS No.1352066-68-2
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

AMG 232AMG 232 is a highly potent, selective and orally bioavailable piperidinone inhibitor of the MDM2-p53 interaction((SPR KD= 0.045 nM, SJSA-1 EdU IC50=9.1 nM).

IC50 value: 9.1 nM (EdU proliferation assay) [1]

Target: MDM2/p53

AMG 232 was an extremely potent MDM2 inhibitor in all assays, especially in the EdU proliferation assay (IC50= 9.1 nM).

Target:MDM-2_p53

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