LY2857785

• Product NameLY2857785
  CAS No.1619903-54-6
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

LY2857785LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.

IC50 value:

Target: CDK9 inhibitor

LY2857785 inhibits the growth of a broad panel of cancer cell lines, and is particularly efficacious in leukemia cells, including orthotopic leukemia preclinical models as well as in ex vivo acute myeloid leukemia and chronic lymphocytic leukemia patient tumor samples.

Target:Na_addition__K_addition_ ATPase

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