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  • Company Name: MedChemexpress LLC
  • Street: 18 Wilkinson Way, Princeton, NJ 08540, USA
  • City: Princeton
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  • Contact Person: Ms.James Gao
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AZD3965

    Detailed Description

    AZD3965AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.

    IC50 value: 1.6 nM(Ki) [1]

    Target: MCT-1 selective inhibitor

    Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1.

    Target:Others

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