AZD3965
Detailed Description
AZD3965AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.
IC50 value: 1.6 nM(Ki) [1]
Target: MCT-1 selective inhibitor
Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1.
Target:Others
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