PD98059

• Product NamePD98059
  CAS No.167869-21-8
  Purity>98%
  Min Quantity
  Price~
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  Molecular Structure

Detailed Description

PD98059PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2.

IC50 value: 2 uM

Target: MEK

in vitro: PD98059 inhibits either basal MEK1 or a partially activated MEK produced by mutation of serine at residues 218 and 222 to glutamate (MEK-2E) with IC50 of 2 μM.

Target:c-Met_HGFR

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