Dabrafenib

• Product NameDabrafenib
  CAS No.1195765-45-7
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

DabrafenibDabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.

IC50 value: 0.8 nM (BRAFV600) [1]

Target: BRAFV600

in vitro: Dabrafenib is selective for Raf kinase, with 400 fold selectivity towards B-Raf over 91% of the other kinases tested.

Target:Calcium Channel

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