Home > Name List By other > [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3, 5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl 2-methylpropyl car...

CAS No 98631-95-9 , [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,
5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl
2-methylpropyl carbonate

  • Name: [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,
    5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl
    2-methylpropyl carbonate
  • Synonyms: BRN 6031322; Sobuzoxanum [INN-Latin];[4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,
    5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl
    2-methylpropyl carbonate;Perazolin; MST 16; MST-16; 98631-95-9; NCGC00015954-02; Sobuzoxano [INN-Spanish];
  • CAS Registry Number:
  • Flash Point: 355.9°C
  • Boiling Point: 664.9°C at 760 mmHg
  • Density: 1.272g/cm3
  • Refractive index: 1.513
  • Flash Point: 355.9°C
  • Molecular Weight: 514.52616
  • InchiKey: OCOKWVBYZHBHLU-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H34N4O10/c1-15(2)11-33-21(31)35-13-25-17(27)7-23(8-18(25)28)
    5-6-24-9-19(29)26(20(30)10-24)14-36-22(32)34-12-16(3)4/h15-16H,5-14H2,
    1-4H3
  • Molecular Formula: C22H34N4O10
  • Molecular Structure:CAS No:98631-95-9 [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,<br />5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl<br />2-methylpropyl carbonate

Related products

Search by region :

Select to

98631-95-9 Sobuzoxane

Contact Supplier

98631-95-9 Sobuzoxane

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

98631-95-9 Sobuzoxane

  • China ZHEJIANG HOLYPHARM BIOTECH CO.,LTD [Manufacturers]
  • Tel: 86-533-8585678
  • Fax: 86-57187357695
  • Address: Room C 13th Floor, West Wing International Garden, No.160 Tianmushan Road, Xihu District, Hangzhou City, China null,nullChina
Contact Supplier

98631-95-9 SOBUZOXANE

  • China Apichem Chemical Technology Co., Ltd [Manufacturer]
  • Tel: 86-137-6120-5405/ 86-21-3762-3285
  • Address: Apichem Chemical Technology Co., Ltd
    room 102, No.22,lane 288,
    Qianshao Road,
    Pudong, shanghai 201201 China null,nullChina
Contact Supplier

98631-95-9 Sobuzoxane

  • China Zhejiang Holypharm Biotech Co., Ltd. [Manufacturers]
  • Tel: +86-(571)-8848-0226
  • Fax: +86-(571)-8735-7695
  • Address: Room C 13th Floor, West Wing International Garden, No.160 Tianmushan Road, Xihu District, Hangzhou, Zhejiang, HANGZHOU,ZHEJIANGChina
Contact Supplier

Select to

1/1
References of [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,
5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl
2-methylpropyl carbonate
Title: Sobuzoxane
CAS Registry Number: 98631-95-9
CAS Name: 1,2-Ethanediylbis[(2,6-dioxo-4,1-piperazinediyl)methylene]carbonic acid bis(2-methylpropyl) ester
Synonyms: 4,4￠-ethylenebis[1-(hydroxymethyl)-2,6-piperazinedione] bis(isobutyl carbonate) (ester); 4,4￠-(1,2-ethanediyl)bis(1-isobutoxycarbonyloxymethyl)-2,6-piperazinedione; 1,2-bis(4-isobutoxycarbonyloxymethyl-3,5-dioxopiperazin-1-yl)ethane
Manufacturers' Codes: MST-16
Trademarks: Perazolin (Zenyaku Kogyo)
Molecular Formula: C22H34N4O10
Molecular Weight: 514.53
Percent Composition: C 51.35%, H 6.66%, N 10.89%, O 31.10%
Literature References: Noncleavable complex-stabilizing DNA topoisomerase II inhibitor. Prepn: J.-C. Cai, M. Takase, EP 140327; eidem, US 4650799 (1985, 1987 both to Zenyaku Kogyo); idem et al., Chem. Pharm. Bull. 37, 2976 (1989). Antitumor activity: T. Narita et al., Cancer Chemother. Pharmacol. 28, 235 (1991). Clinical evaluation in non-Hodgkin's lymphoma: R. Ohno et al., J. Natl. Cancer Inst. 84, 435 (1992); in adult T-cell leukemia-lymphoma: idem et al., Cancer 71, 2217 (1993). Acute toxicity study: T. Tokiwa et al., Iyakuhin Kenkyu 22, 435 (1991). C.A. 115, 222916k (1991).
Properties: Crystals from ethylene glycol monomethylether, mp 128-130°. Also reported as crystals from ethanol, mp 132-133° (Cai, 1989). Practically insol in water. LD50 in male, female mice, rats (mg/kg): 807, 960, 877, 567 i.p.; 400, 673, 3025, 2821 s.c.; >5 g/kg orally in all species (Tokiwa).
Melting point: mp 128-130°; mp 132-133° (Cai, 1989)
Toxicity data: LD50 in male, female mice, rats (mg/kg): 807, 960, 877, 567 i.p.; 400, 673, 3025, 2821 s.c.; >5 g/kg orally in all species (Tokiwa)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Topoisomerase II Inhibitor.