Home > Name List By other > (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2, 3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3, 3-dimethyl-7-oxo-4-thia-1-aza...

CAS No 61477-96-1 , (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,
3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,
3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

  • Name: (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,
    3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,
    3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • Synonyms: Pipracil; Peperacillin;Pipracil;(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,
    3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,
    3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Piperacillin anhydrous; CHEBI:8232; Piperacillin Monosodium Salt; Piper; Pipril; 61477-96-1; Pipercillin;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.51 g/cm3
  • Water Solubility: soluble in water
  • Flash Point: °C
  • EINECS: 262-811-8
  • Molecular Weight: 517.55478
  • InchiKey: IVBHGBMCVLDMKU-GXNBUGAJSA-N
  • InChI: InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-
    5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,
    20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1
  • Molecular Formula: C23H27N5O7S
  • Molecular Structure:CAS No:61477-96-1 (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,<br />3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,<br />3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

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61477-96-1 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-

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61477-96-1 PIPERACILLIN

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61477-96-1 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-

  • China Hangzhou Starshine Pharmaceutical Co., LTD [Manufacturers]
  • Tel: +86-571-89939756 85122191
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61477-96-1 Piperacillin

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
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61477-96-1 Piperacillin

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
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61477-96-1 Piperacillin

  • United States Tecoland Corporation null
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  • China Melone Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-41182593631/ +86-41182702105
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  • Address: Room 2209,No.232, Jinma Road,
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61477-96-1 piperacillin

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61477-96-1 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-

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61477-96-1 PIPERACILLIN

  • United States Haorui Pharma-Chem Inc. [Manufacturer]
  • Tel: 732-906-7666
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  • Address: Haorui Pharma-Chem Inc.
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References of (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,
3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,
3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Title: Piperacillin
CAS Registry Number: 61477-96-1
CAS Name: (2S,5R,6R)-6-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Synonyms: (2S,5R,6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-D(-)-a-(4-ethyl-2,3-dioxo-1-piperazinylcarbonylamino)-a-phenylacetamidopenicillanic acid; 4-ethyl-2,3-dioxopiperazine carbonyl ampicillin
Molecular Formula: C23H27N5O7S
Molecular Weight: 517.55
Percent Composition: C 53.38%, H 5.26%, N 13.53%, O 21.64%, S 6.20%
Literature References: Broad spectrum semi-synthetic antibiotic related to pencillin. Prepn: I. Saikawa et al., DE 2519400; eidem, US 4087424 (1976, 1978 both to Toyama). In vitro studies: G. P. Bodey, B. LeBlanc, Antimicrob. Agents Chemother. 14, 78 (1978); R. Wise et al., ibid. 549. In vitro and in vivo: N. A. Kuck, G. S. Redin, J. Antibiot. 31, 1175 (1978). Pharmacokinetics: M. A. Evans et al., J. Antimicrob. Chemother. 4, 255 (1978). Metabolism: K. Iida et al., Antimicrob. Agents Chemother. 14, 257 (1978). Clinical study: T. Saito, Y. Yamada, Jpn. J. Antibiot. 30, 835 (1977). Toxicity study: A. Takai et al., Chemotherapy (Tokyo) 25, 816 (1977). Review of antibacterial activity, pharmacokinetics: G. L. Mandell, Clin. Ther. 7, Suppl. B, 28-35 (1985). Review of clinical experience in urinary tract infections: S. J. Childs, ibid. 36-45. Series of articles on antibacterial activity and clinical use: Chemotherapy (Tokyo) 36, Suppl. 7, 1-85 (1988).
 
Derivative Type: Sodium salt
CAS Registry Number: 59703-84-3
Manufacturers' Codes: CL-227193; T-1220
Trademarks: Isipen (Krka); Pentcillin (Toyama-Sankyo); Pipracil (Wyeth); Pipril (Wyeth)
Molecular Formula: C23H26N5NaO7S
Molecular Weight: 539.54
Percent Composition: C 51.20%, H 4.86%, N 12.98%, Na 4.26%, O 20.76%, S 5.94%
Properties: mp 183-185° (dec). LD50 in mice, rats, dogs, monkeys (g/kg): 5, 2.7, >6, >4 i.v. (Takai).
Melting point: mp 183-185° (dec)
Toxicity data: LD50 in mice, rats, dogs, monkeys (g/kg): 5, 2.7, >6, >4 i.v. (Takai)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.