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CAS No 65141-46-0 , 2-(pyridine-3-carbonylamino)ethyl nitrate

  • Name: 2-(pyridine-3-carbonylamino)ethyl nitrate
  • Synonyms: Nicorandilum; 65141-46-0; Ikorel; Sigmart; 2-Nicotinamidoethyl nitrate;Dancor; SG-75; Adancor;2-(pyridine-3-carbonylamino)ethyl nitrate; Nikoran;
  • CAS Registry Number:
  • Melting Point: 92 ºC
  • Density: 1.331 g/cm3
  • Refractive index: 1.547
  • EINECS: 265-514-1
  • Molecular Weight: 211.17476
  • InchiKey: LBHIOVVIQHSOQN-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H9N3O4/c12-8(7-2-1-3-9-6-7)10-4-5-15-11(13)14/h1-3,6H,4-5H2,
    (H,10,12)
  • Molecular Formula: C8H9N3O4
  • Molecular Structure:CAS No:65141-46-0 2-(pyridine-3-carbonylamino)ethyl nitrate
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65141-46-0 nicorandil

  • China Syntechem Co.,Ltd [Manufacturer]
  • Tel: +86-519-89882658
  • Fax: +86-519-8512 5369
  • Address: Syntechem Co.,Ltd
    18 South Zhulin Rd.
    Tianning district,Changzhou
    Jiangsu China 213022 ,China
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65141-46-0 Nicorandil

  • IUPAC NAME-2-[(pyridin-3-ylcarbonyl)amino]ethyl nitrate MOLECULAR FORMULA-C8H9N3O4 MOLAR MASS-211.175 g/mol Nicorandil is a vasodilatory drug used to treat angina.
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
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  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

65141-46-0 Nicorandil

  • Nicorandil
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
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65141-46-0 N-[2-(Nitroxy)ethyl]-3-pyridinecarboxamide

  • N-[2-(Nitroxy)ethyl]-3-pyridinecarboxamide
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
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  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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65141-46-0 nicorandil

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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65141-46-0 Nicorandil

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65141-46-0 Nicorandil

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
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  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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65141-46-0 nicorandil

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
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  • Address: 1213 JunMin Road,Pudong,China ,China
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65141-46-0 Nicorandil

  • Nicorandil
  • China Pharmasi Chemicals Co.Ltd [Manufacturer]
  • Tel: +86-21-67752521
  • Fax: +86-21-57819315
  • Address: Pharmasi Chemicals Co.Ltd
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65141-46-0 nicorandil

  • China shanghai sphchem co.,ltd [Manufacturers]
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  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
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References of 2-(pyridine-3-carbonylamino)ethyl nitrate
Title: Nicorandil
CAS Registry Number: 65141-46-0
CAS Name: N-[2-(Nitrooxy)ethyl]-3-pyridinecarboxamide
Synonyms: N-(2-hydroxyethyl)nicotinamide nitrate (ester)
Manufacturers' Codes: SG-75
Trademarks: Adancor (Merck-Cl¢enot); Ikorel (RPR); Perisalol (Chugai); Sigmart (Chugai)
Molecular Formula: C8H9N3O4
Molecular Weight: 211.17
Percent Composition: C 45.50%, H 4.30%, N 19.90%, O 30.31%
Literature References: Nicotinamide derivative; exhibits dual mechanism of action as both nitrovasodilator and potassium channel activator. Prepn: H. Nagano et al., DE 2714713; eidem, US 4200640 (1977, 1980 both to Chugai). Pharmacology: N. Taira et al., Clin. Exp. Pharmacol. Physiol. 6, 301 (1979). Mechanism of action: F. Yoneyama et al., Cardiovasc. Drugs Ther. 4, 1119 (1990). Symposia on pharmacology and clinical efficacy: Am. J. Cardiol. 63, Suppl, 1J-85J (1989); J. Cardiovasc. Pharmacol. 20, Suppl. 3, S1-S108 (1992). Review of clinical potential in ischemic heart disease: H. Purcell, K. Fox, Br. J. Clin. Pract. 47, 150-154 (1993). Clinical prevention of coronary events in patients with angina: IONA Study Group, Lancet 359, 1269 (2002).
Properties: Colorless needles from ether/ethanol, mp 92-93°. LD50 in rats (mg/kg): 1200-1300 orally; 800-1000 i.v. (Nagano).
Melting point: mp 92-93°
Toxicity data: LD50 in rats (mg/kg): 1200-1300 orally; 800-1000 i.v. (Nagano)
Therap-Cat: Antianginal.
Keywords: Antianginal; Potassium Channel Activator/Opener.