Home > Name List By 1 > 1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

CAS No 50-89-5 , 1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

  • Name: 1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • Synonyms: 2'-Deoxythymidine; deoxythymidine;1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5-Methyl-2'-deoxyuridine; Thymine-2-deoxyriboside; 50-89-5; 5-Methyldeoxyuridine; Thymidin;
  • CAS Registry Number:
  • Melting Point: 187-189 ºC
  • Density: 1.452 g/cm3
  • Alpha: 18.6 º (C=3, H2O)
  • Safety Statements: S22;S24/25;S37/39;S26
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 200-070-4
  • Molecular Weight: 242.22856
  • InchiKey: IQFYYKKMVGJFEH-XLPZGREQSA-N
  • InChI: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,
    6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
  • Risk Statements: S22;S24/25
  • Molecular Formula: C10H14N2O5
  • Molecular Structure:CAS No:50-89-5 1-[(2R,4S,<br />5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
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50-89-5 Thymine deoxyriboside

  • Used as a pharmaceutical intermediate to synthesize antiviral and anti-hiv drugs. It is mainly used in the preparation of anti-aids drugs (such as zidovudine). Hybrid tumor fusion, ion and cloning for HT and HAT cocktail method. A nucleoside used in ...
  • China Haorui Industrial Dev.Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-755-82960263
  • Fax: 86-755-82960262
  • Address: Rm.904-906,First Tower A,Yi Tian Rd,Futian District shenzhen,GuangdongChina
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50-89-5 Stavudine intermediate

  • Stavudine intermediate 1-[2-Deoxy-beta-D-ribofuranosyl]-5-methyluracil); 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-; 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-ribofuranosyl)-5-methyl-; 2'-Deoxythymidine; 5-Met...
  • Min. Order: 10
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  • China Honrok BiotechCo.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-531-69952680
  • Address: No 10 Huaneng Road Lixia District Jinan,ShandongChina
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50-89-5 Thymidine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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50-89-5 Thymidine

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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50-89-5 Beta-Thymidine

  • China Shanghai Hanhong Chemical Co., Ltd. [, Manufacturer, Trading Company, Agent]
  • Tel: +86-(21)-64762736, 64531573
  • Fax: +86-(21)-54291107
  • Address: 206-209, NO.1 Building , NO.245,Jiachuan Road, Xuhui District, Shanghai, Xuhui District,ShanghaiChina
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50-89-5 Thymidine

  • China SHANGHAI HANHONG CHEMICAL CO.,LTD. [Manufacturers]
  • Tel: 021-64545202
  • Fax: 021-54291107
  • Address: Room 207, Zenghe Building , No.245, Jiachuan Road, Xuhui District, Shanghai, China shanghai,shanghaiChina
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50-89-5 Thymidine

  • China BINHAI HANHONG BIOCHEMICAL CO., LTD. [Manufacturers]
  • Tel: +86-21-54302127
  • Fax: +86-21-54291107
  • Address: Room 209,Zonghe Building ,Jiachuan Road 245, Xuhui District, Shanghai, China Shanghai,ShanghaiChina
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50-89-5 Thymidine

  • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
  • Tel: +86-571-85395792
  • Fax: +86-571-85420103
  • Address: 607, North Zhongshan Road, Hangzhou 310000 China ,ZhejiangChina
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50-89-5 A3328 D-THYMIDINE

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK ,United Kingdom
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50-89-5 Thymidine

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References of 1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Title: Thymidine
CAS Registry Number: 50-89-5
Synonyms: 1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil; thymine-2-desoxyriboside
Molecular Formula: C10H14N2O5
Molecular Weight: 242.23
Percent Composition: C 49.58%, H 5.83%, N 11.56%, O 33.03%
Literature References: Constituent of deoxyribonucleic acid, q.v. Isoln from thymonucleic acid: Levene, London, J. Biol. Chem. 83, 793 (1929). Structure: Levene, Tipson, ibid. 109, 623 (1935). Conformation: Lemieux, Can. J. Chem. 39, 116 (1961); Tollin et al., Nature 217, 1148 (1968). Prepn of thymidine-3¢-phosphate and of thymidine-5¢-phosphate: Tener, J. Am. Chem. Soc. 83, 165 (1961). Review: Basic Principles in Nucleic Acid Chemistry vol. 1, P. O. P. Ts'o, Ed. (Academic Press, New York, 1974) passim.
Properties: Rosettes of needles from ethyl acetate. mp 185°. Yields a sublimate of thymine when heated. [a]D25 +30.6° (c = 1.029). uv max (pH 7.2): 206.5, 267 nm (e ′ 10+3 9.8, 9.7). Absorption spectra: D. Voet et al., Biopolymers 1, 193 (1963). Sol in water, methanol, hot alcohol, hot acetone, hot ethyl acetate, pyridine, glacial acetic acid; sparingly sol in hot chloroform.
Melting point: mp 185°
Optical Rotation: [a]D25 +30.6° (c = 1.029)
Absorption maximum: uv max (pH 7.2): 206.5, 267 nm (e ′ 10+3 9.8, 9.7)
 
Derivative Type: Monotrityl thymidine
Molecular Formula: C29H28N2O5
Molecular Weight: 484.54
Percent Composition: C 71.88%, H 5.82%, N 5.78%, O 16.51%
Properties: Prepd by the action of triphenylmethyl chloride on thymidine in pyridine. mp 125°. [a]D24 +11.4° (c = 1.01 in acetone).
Melting point: mp 125°
Optical Rotation: [a]D24 +11.4° (c = 1.01 in acetone)