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CAS No 50-89-5 , 1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Search by region : India

  • Name: 1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • Synonyms: 2'-Deoxythymidine; deoxythymidine;1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5-Methyl-2'-deoxyuridine; Thymine-2-deoxyriboside; 50-89-5; 5-Methyldeoxyuridine; Thymidin;
  • CAS Registry Number:
  • Melting Point: 187-189 ºC
  • Density: 1.452 g/cm3
  • Alpha: 18.6 º (C=3, H2O)
  • Safety Statements: S22;S24/25;S37/39;S26
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 200-070-4
  • Molecular Weight: 242.22856
  • InchiKey: IQFYYKKMVGJFEH-XLPZGREQSA-N
  • InChI: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,
    6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
  • Risk Statements: S22;S24/25
  • Molecular Formula: C10H14N2O5
  • Molecular Structure:CAS No:50-89-5 1-[(2R,4S,<br />5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

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50-89-5 Beta-Thymidine

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  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
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50-89-5 Thymidine

  • India Nile Chemicals [Manufacturers]
  • Tel: +91-(22)-66313162, 23454828
  • Fax: +91-(22)-23454828
  • Address: 202, Matruchhaya, 378/80 Narshi Natha Street, Mumbai, Maharashtra 400 009, Mumbai,MumbaiIndia
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References of 1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Title: Thymidine
CAS Registry Number: 50-89-5
Synonyms: 1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil; thymine-2-desoxyriboside
Molecular Formula: C10H14N2O5
Molecular Weight: 242.23
Percent Composition: C 49.58%, H 5.83%, N 11.56%, O 33.03%
Literature References: Constituent of deoxyribonucleic acid, q.v. Isoln from thymonucleic acid: Levene, London, J. Biol. Chem. 83, 793 (1929). Structure: Levene, Tipson, ibid. 109, 623 (1935). Conformation: Lemieux, Can. J. Chem. 39, 116 (1961); Tollin et al., Nature 217, 1148 (1968). Prepn of thymidine-3¢-phosphate and of thymidine-5¢-phosphate: Tener, J. Am. Chem. Soc. 83, 165 (1961). Review: Basic Principles in Nucleic Acid Chemistry vol. 1, P. O. P. Ts'o, Ed. (Academic Press, New York, 1974) passim.
Properties: Rosettes of needles from ethyl acetate. mp 185°. Yields a sublimate of thymine when heated. [a]D25 +30.6° (c = 1.029). uv max (pH 7.2): 206.5, 267 nm (e ′ 10+3 9.8, 9.7). Absorption spectra: D. Voet et al., Biopolymers 1, 193 (1963). Sol in water, methanol, hot alcohol, hot acetone, hot ethyl acetate, pyridine, glacial acetic acid; sparingly sol in hot chloroform.
Melting point: mp 185°
Optical Rotation: [a]D25 +30.6° (c = 1.029)
Absorption maximum: uv max (pH 7.2): 206.5, 267 nm (e ′ 10+3 9.8, 9.7)
 
Derivative Type: Monotrityl thymidine
Molecular Formula: C29H28N2O5
Molecular Weight: 484.54
Percent Composition: C 71.88%, H 5.82%, N 5.78%, O 16.51%
Properties: Prepd by the action of triphenylmethyl chloride on thymidine in pyridine. mp 125°. [a]D24 +11.4° (c = 1.01 in acetone).
Melting point: mp 125°
Optical Rotation: [a]D24 +11.4° (c = 1.01 in acetone)