Home > Name List By 5 > 5-fluoro-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

CAS No 50-91-9 , 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

  • Name: 5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • Synonyms: Floxuridin; FUDR; Fluorodeoxyuridine; Deoxyfluorouridine;5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 50-91-9;2'-Deoxy-5-fluorouridine; Fluoruridine deoxyribose; 5-Fluorodeoxyuridine;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 148-153 ºC
  • Density: 1.64 g/cm3
  • Refractive index: 1.608
  • Alpha: 35.9 º (C=1, WATER)
  • Safety Statements: R22;R36/37/38;R68
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-072-5
  • Molecular Weight: 246.192443
  • InchiKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
  • InChI: InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,
    5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
  • Risk Statements: S26;S36/37/39
  • Molecular Formula: C9H11FN2O5
  • Molecular Structure:CAS No:50-91-9 5-fluoro-1-[(2R,4S,<br />5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Search by region :

Select to

50-91-9 Floxuridine

  • CAS Number:50-91-9 Name: Floxuridine Formula: C9H11FN2O5 Synonyms: 1-(2-Deoxy-b-D-ribofuranosyl)-5-fluorouracil;5-Fluoro-2'-deoxy-b-uridine;5-Fluoro-2'-deoxyuridine;5-Fluorodeoxyuridine;5-Fluorouracil 2'-deoxyriboside;5-Fluorouracil deoxyriboside;Flo...
  • China Tocopharm Co.,Ltd. [Manufacturer, Other]
  • Tel: 86-021-31608287
  • Fax: 86-021-60919354
  • Address: RM506, No.80,Yichuan Rd.,Putuo District Shanghai,ShanghaiChina

50-91-9 (+)-5-Fluoro-2'-deoxyuridine

  • product Name (+)-5-Fluoro-2'-deoxyuridine Synonyms Deoxyfluorouridine,98%; 5-Fluoro-2-deoxyuridine; FUDR; 5-Fluoro-2?Deoxy Uridine; 2-Deoxy-5-fluorouridine; Floxuridine; 5-FUDR; (+)-5-Fluoro-2?deoxyuridine; 1-(2-deoxypentofuranosyl)-5-fluoropyrimidin...
  • China Hangzhou Merry Chemical Co.,Ltd [Trading Company]
  • Tel: 86-182-57110923
  • Fax: --
  • Address: 233 Wensan Road , Xihu Area , Hangzhou hangzhu,ZhejiangChina
Contact Supplier

50-91-9 5-Fluoro-2'-deoxyuridine

  • 5-Fluoro-2'-deoxyuridine
  • Germany chemcube UG [Manufacturer]
  • Tel: +49 (22 08) 7 75 04 06
  • Fax: +49 (22 08) 7 75 02 30 /
    +49 (32 12) 1 00 74 76
  • Address: chemcube UG
    Salierweg 1
    53859 Niederkassel
    Germany ,Germany
Contact Supplier

50-91-9 (+)-5-Fluoro-2'-deoxyuridine

Contact Supplier

50-91-9 5-Fluoro-2'-deoxyuridine

  • 5-Fluoro-2'-deoxyuridine, 98%
  • United States INDOFINE Chemical Co., Inc. [Manufacturer]
  • Tel: (908) 359-6778
  • Fax: (908) 359-1179
  • Address: 121 Stryker Lane
    Bldg 30, Suite 1
    Hillsborough, NJ 08844 ,United States
Contact Supplier

50-91-9 (+)-5-Fluoro-2'-deoxyuridine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
Contact Supplier

50-91-9 (+)-5-Fluoro-2-deoxyuridine

  • (+)-5-Fluoro-2-deoxyuridine
  • Switzerland CONNECT MARKETING GMBH [Manufacturer]
  • Tel: +41 81 740 58 50
  • Fax: +41 81 740 58 51
  • Address: CONNECT MARKETING GMBH
    BAHNWEG NORD 35
    CH-9475 SEVELEN/SG
    SWITZERLAND ,Switzerland
Contact Supplier

50-91-9 5-Fluoro-2'-deoxyuridine

  • 5-Fluoro-2'-deoxyuridine
  • United States Chem-Impex International, Inc. [Manufacturer]
  • Tel: 630 766 2112
  • Fax: 630 766 2218
  • Address: 935 Dillon Drive Wood Dale IL 60191 USA ,United States
Contact Supplier

50-91-9 (+)-5-Fluoro-2'-deoxyuridine

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
Contact Supplier

50-91-9 1-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1H,3H)-dione

  • 1-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1H,3H)-dione, 97
  • United Kingdom Atlantic Research Chemicals Ltd [Manufacturer]
  • Tel: +44-8707 746454
  • Fax: +44-8707 756455
  • Address: Atlantic Research Chemicals Ltd
    Unit A, Stratton View Business Park
    Holsworthy Road
    Stratton
    Bude
    Cornwall EX23 9NR
    UK ,United Kingdom
Contact Supplier

Select to

References of 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Title: Floxuridine
CAS Registry Number: 50-91-9
CAS Name: 2¢-Deoxy-5-fluorouridine
Synonyms: 1-(2-deoxy-b-D-ribofuranosyl)-5-fluorouracil; 5-fluoro-2¢-deoxy-b-uridine
Manufacturers' Codes: NSC-27640
Trademarks: FUDR (Roche)
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Percent Composition: C 43.91%, H 4.50%, F 7.72%, N 11.38%, O 32.49%
Literature References: Prepn: Hoffer et al., J. Am. Chem. Soc. 81, 4112 (1959); Heidelberger, Duschinsky, US 2885396 (1959); Duschinsky et al., US 2970139 (1961); Hoffer, US 2949451; US 3041335 (1960, 1962 both to Hoffmann-La Roche). Structure: Lemieux, Hoffer, Can. J. Chem. 39, 110 (1961). Crystal and molecular structure: Harris, Diss. Abstr. 24, 4425 (1964); Harris, McIntyre, Biophys. J. 4, 203 (1964). Conformation of furanose ring in molecule: Sundaralingam, J. Am. Chem. Soc. 87, 599 (1965).
Properties: Crystals from butyl acetate, mp 150-151° (Hoffer, 1959); also reported as mp 145° (US 3041335). [a]D +37° (water), +48.6° (DMF). uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480).
Melting point: mp 150-151° (Hoffer, 1959); mp 145° (US 3041335)
Optical Rotation: [a]D +37° (water), +48.6° (DMF)
Absorption maximum: uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480)
 
Derivative Type: a-Anomer
Synonyms: 1-(2-Deoxy-a-D-erythro-pentofuranosyl)-5-fluorouracil
Properties: Crystals from butyl acetate, mp 150-151°. [a]D25 -21° (c = 2 in water).
Melting point: mp 150-151°
Optical Rotation: [a]D25 -21° (c = 2 in water)
 
Therap-Cat: Antiviral; antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs; Antiviral; Purines/Pyrimidinones.