Home > Name List By 6 > 6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-te...

CAS No 483-17-0 , 6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-,(1R)-

  • Name: 6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-,(1R)-
  • Synonyms: Desmethylemetine;Cephaeline(6CI,7CI,8CI); Emetan-6'-ol, 7',10,11-trimethoxy-;7',10,11-Trimethoxyemetan-6'-ol;6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-,(1R)-; Cepheline;Dihydropsychotrine; (-)-Cephaeline;
  • CAS Registry Number:
  • Transport: 1544
  • Melting Point: 115-1160C
  • Flash Point: 325.1°C
  • Boiling Point: 614°Cat760mmHg
  • Density: 1.21g/cm3
  • Refractive index: 1.614
  • Safety Statements:
    RIDADR 1544
    HazardClass 6.1(b)
    PackingGroup III
  • Flash Point: 325.1°C
  • EINECS: 207-591-6
  • Molecular Weight: 0
  • InChI: InChI=1/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1
  • Molecular Formula: C28H38 N2 O4
  • Molecular Structure:CAS No:483-17-0 6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-,(1R)-

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483-17-0 CEPHAELINE

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany null,nullGermany
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483-17-0 CEPHALIN ANIMAL

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
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  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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483-17-0 Cephaeline

  • Cephaeline
  • United States Medical Isotopes, Inc. [Manufacturer]
  • Tel: (603) 635-2255/ (800) 374-9513
  • Fax: (603) 635-2448
  • Address: 100 Bridge Street
    Pelham, NH 03076 null,nullUnited States
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483-17-0 Cephalin (animal)

  • Cephalin (animal)
  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
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483-17-0 CEPHALIN BR

  • CEPHALIN BR
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
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    Hong Kong null,nullHong kong
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483-17-0 CEPHALIN (ANIMAL)

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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References of 6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-,(1R)-
Title: Cephaeline
CAS Registry Number: 483-17-0
CAS Name: 7￠,10,11-Trimethoxyemetan-6￠-ol
Synonyms: desmethylemetine; dihydropsychotrine
Molecular Formula: C28H38N2O4
Molecular Weight: 466.61
Percent Composition: C 72.07%, H 8.21%, N 6.00%, O 13.72%
Literature References: Next to emetine the most important alkaloid of ipecac, the ground roots of Uragoga ipecacuanha (Brot.) Baill. [Cephaelis ipecacuanha (Brot.) A. Rich.], Rubiaceae: Carr, Pyman, J. Chem. Soc. 105, 1591 (1914); Hesse, Ann. 405, 1 (1914). Structure: Pailer, Porschinski, Monatsh. Chem. 80, 101 (1949). Stereochemistry: Van Tamelen et al., J. Am. Chem. Soc. 79, 4817 (1957). Partial synthesis: A. K. Garg, J. R. Gear, Tetrahedron Lett. 50, 4377 (1969). Biosynthetic studies: eidem, ibid. 1968, 141. HPLC determn in biological fluids: D. J. Crouch et al., J. Anal. Toxicol. 8, 63 (1984). Review: M. Janot in Manske, Holmes, The Alkaloids vol. 3 (Academic Press, New York, 1953) pp 363-394.
Properties: Needles from ether. Faintly bitter taste. mp 115-116°. [a]D20 -43.4° (c = 2 in chloroform). Practically insol in water. Freely sol in dil hydrochloric acid, dil sulfuric acid, acetic acid, methanol, ethanol, acetone, chloroform. Less sol in ether, petr ether.
Melting point: mp 115-116°
Optical Rotation: [a]D20 -43.4° (c = 2 in chloroform)
 
Derivative Type: Dihydrochloride heptahydrate
Molecular Formula: C28H40Cl2N2O4.7H2O
Molecular Weight: 665.64
Percent Composition: C 50.52%, H 8.18%, Cl 10.65%, N 4.21%, O 26.44%
Properties: Prisms, sinters at 245°, slowly melts up to 270°. [a]D20 +25.0° (c = 2). Sol in water. Solns turn yellow. Less sol in alc, acetone, chloroform. Practically insol in benzene, ligroin.
Optical Rotation: [a]D20 +25.0° (c = 2)
 
Derivative Type: Dihydrobromide heptahydrate
Molecular Formula: C28H40Br2N2O4.7H2O
Molecular Weight: 754.54
Percent Composition: C 44.57%, H 7.21%, Br 21.18%, N 3.71%, O 23.32%
Properties: Prisms from dil hydrobromic acid, sinters at 266°, slowly melts up to 293°. Sol in water; moderately sol in alcohol, acetone. Practically insol in benzene.
 
Derivative Type: Methyl ether see Emetine
 
Therap-Cat: Emetic; antiamebic.
Therap-Cat-Vet: Has been used as an emetic and expectorant.
Keywords: Antiamebic; Emetic.