Home > Name List By 4 > 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2, 3-dihydro-1-benzofuran-7-carboxamide

CAS No 179474-81-8 , 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,
3-dihydro-1-benzofuran-7-carboxamide

  • Name: 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,
    3-dihydro-1-benzofuran-7-carboxamide
  • Synonyms: 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide;179474-81-8;4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,
    3-dihydro-1-benzofuran-7-carboxamide;
  • CAS Registry Number:
  • Flash Point: 244.9°C
  • Boiling Point: 481.4°Cat760mmHg
  • Density: 1.28
  • Refractive index: 1.599
  • Flash Point: 244.9°C
  • Molecular Weight: 367.87034
  • InchiKey: ZPMNHBXQOOVQJL-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)
    16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)
  • Molecular Formula: C18H26ClN3O3
  • Molecular Structure:CAS No:179474-81-8 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,<br />3-dihydro-1-benzofuran-7-carboxamide

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References of 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,
3-dihydro-1-benzofuran-7-carboxamide
Title: Prucalopride
CAS Registry Number: 179474-81-8
CAS Name: 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide
Manufacturers' Codes: R-93877
Trademarks: Resolor (J & J)
Molecular Formula: C18H26ClN3O3
Molecular Weight: 367.87
Percent Composition: C 58.77%, H 7.12%, Cl 9.64%, N 11.42%, O 13.05%
Literature References: Benzofuran derivative; specific serotonin 5-HT4 receptor agonist. Prepn: G. H. P. Van Daele et al., WO 9616060; eidem, US 5854260 (1996, 1998 both to Janssen). Effect on isolated gastrointestinal muscle: N. H. Prins et al., Br. J. Pharmacol. 127, 1431 (1999). Clinical stimulation of colonic transit: E. P. Bouras et al., Gut 44, 682 (1999).
Properties: Monohydrate, mp 90.7°.
Melting point: mp 90.7°
Therap-Cat: Gastroprokinetic.
Keywords: Gastroprokinetic.