Superoxide dismutase

• Product NameSuperoxide dismutase
  CAS No.9054-89-1
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Detailed Description

Name:Superoxide dismutase
Synonyms:SOD
CAS Registry Number:9054-89-1
Appearance: white powder
Assay: NLT 98%
Use:SOD has powerful antiinflammatory activity. For example, SOD is highly effective in treatment of colonic inflammation in experimental colitis. Treatment with SOD decreasesreactive oxygen species generation and oxidative stress and, thus, inhibits endothelial activation and indicate that modulation of factors that govern adhesion molecule expression and leukocyte-endothelial interactions. Therefore, such as antioxidants may be important new therapies for the treatment of inflammatory bowel disease.
Similarly, SOD has multiple pharmacological activities. E.g., it ameliorates cis-platinum-induced nephrotoxicity in rodents . As "Orgotein" or "ontosein", a pharmacologically-active purified bovine liver SOD, it is also effective in the treatment of urinary tract inflammatory disease in man . For a time, bovine liver SOD even had regulatory approval in several European countries for such use. This was truncated, apparently by concerns about prion disease.

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• Superoxide dismutase