Triptorelin
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Molecular Structure
Detailed Description
Triptorelin,Hormone Peptides Triptorelin , a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) , is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts . By causing constant stimulation of the pituitary , it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH) . Like other GnRH agonists , triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer , precocious puberty , estrogen-dependent conditions (such as endometriosis or uterine fibroids) , and in assisted reproduction .
Triptorelin,It is also used as therapy in cases of gender dysphoria . Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals) . In the United States , it is sold by Watson Pharmaceuticals as Trelstar . In Iran Triptorelin is marketed under the brand name Variopeptyl (Varian Darou Pajooh).
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