Letrozole (Femara)
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Molecular Structure
Detailed Description
Letrozole (Femara)
Synonyms: 4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile;Femara
CAS: 112809-51-5
MF: C17H11N5
MW: 285.3
Product Categories: Anti-Cancer;Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Letrozole;Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Antibiotics;Aromatics;Heterocycles
Chemical Properties: white to light yellow crystal
Usage: A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic .
Packing:1kg/foil bag or as required
Tests Specifications Results
Appearance White or off-white crystaline powder White Crystalline powder
Solubility Soluble in Chloroform; Soluble in ethanol when heated Conform
ldentification (1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm Conform Conform
(2)Infrared spectrum should be in accordance the dominant peak of contrast In accordance with the dominant peak of contrast
Melting points 182oC-184oC 182oC
Related substances ≤0.5% 0.3%
Single impurity ≤0.3% 0.2%
Loss on drying ≤1.0% 0.8%
[Assay]C17H11N5 (On anhydrous basis) ≥98.0% 99.2%
Conclusion Conforms Specifications of Enterprise Standard.
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- Letrozole (Femara)