Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd

You are here: HomeProductsEthynodiol diacetate

Contact us

  • Company Name: Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd
  • Street: Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd
  • City: Wuhan
  • Province/state: Hubei
  • Country/region: China
  • Contact Person: Ms.Charlotte Xie
  • Tel: 86-027-50756237
  • Fax: 86-027-50756237
  • Email:

Ethynodiol diacetate

  • CAS No:297-76-7 [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,<br />9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]<br />acetate
    Molecular Structure

    Detailed Description


    Quick Details
    ---------------------------------------
    Ethynodiol diacetate
    Synonyms: (3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol diacetate
    CAS: 297-76-7
    Molecular Formula: C6H6O4
    Formula Weight: 142.11
    Appearance: white fine powder

    Description:
    --------------------------------------------
    Ethynodiol diacetate (INN; sold as Continuin, Femulen, Luteonorm, Luto-Metrodiol, and Metrodiol), or ethynodiol diacetate (USAN, BAN), is a steroidal progestin which is used as a hormonal contraceptive. Relative to other 19-nortestosterone derivatives, it has relatively little or no potency as an androgen, and also unlike most progestins in general, has significant estrogenic effects.


    Pharmacology, Interactions, and Contraindications
    --------------------------------------------
    Mechanism of Action

    Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Ethynodiol Diacetate will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.

    Pharmacology

    Ethynodiol Diacetate is used as a female contraceptive. Ethynodiol Diacetate is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Ethynodiol Diacetate tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
  • Ethynodiol diacetate
  • Ethynodiol diacetate