Azithromycin
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Molecular Structure
Detailed Description
Azithromycin
Synonyms:N-methyl-11-aza-10-deoxo-10-dihydroerythromycin a;11-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-2-ethyl-3,4,10-tr;11-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-3,4,10-trihydroxy-14-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,6,8,10,12,13-heptamethyl-1-oxa-6-aza-cyclopentadecan-15-one;9-deoxo-9alpha-methyl-9alpha-aza-homoerythromycin a;9-deoxo-9a-methyl-9a-aza-homoerythromycin a;Azithromycin;Azithromycine;1-oxa-6-azacyclopentadecan-15-one,13-((2,6-dideoxy-3-c-methyl-3-o-methyl-alpha
Cas:83905-01-5
Mf:C38h72n2o12
Mw:748.98
Product categories:Antibiotics;Antibiotic;Antibiotic explorer;Intermediates & fine chemicals;Pharmaceuticals;A - kantibiotics;Antibacterial
Chemical Properties: White Crystalline Powder
Assay:98%
Usage: Azithromycin is a semi-synthetic, ring-expanded erythromycin, produced by a Beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive methylation. Azithromycin was the first of the azalides and was designed to improve stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria. Since its discovery in 1980 by Djokic and co-workers, azithromycin has enjoyed considerable therapeutic success.
Packing:25kg/drum
Test Items Specification Test Results
Charaters White or off-white crystallinity powder Complies
Identification Infrared Absorption HPLC should complies Complies Complies
Specific rotation -45o～-49o -48o
Crystallinity Meets the requirements Complies
PH 9.0～11.0 10.0
Wate 4.0～5.0% 4.5%
Residue on ignition ≤0.3% 0.1%
Heavy metals ≤25ppm <25ppm
Assay 945～1030ug/mg(C38H72N2O12)based on anhydrous substance 965ug/mg
- Azithromycin
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