L-liothyronine
-
Molecular Structure
Detailed Description
L-liothyronine
Synonyms:3,3’,5-triiodothyronine;3,5,3’-triiodothyronine;3’,5-triiodo-l-thyronin;4-(3-iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine;5-diiodophenyl)-3-(4-(4-hydroxy-3-iodophenoxy)-l-alanin;cytomel;l-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine;l-liothyronine
CAS:6893-02-3
MF:C15H12I3NO4
MW:650.97
EINECS:229-999-3
mp:234-238 °C(lit.)
alpha:23 o (c=2 in ethanol)
storage temp.:?20°C
form:powder
Merck:5510
Chemical Properties:Off-White Solid
Usage:Thyroidic drug;Thyroid hormone.One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
Item Specification Result
Appearance An odorless, almost white or buff colored powder pass
Solubility 1,Very slightly soluble in water pass
2,slightly soluble in alcohol pass
3,practically insoluble in most other organic solvents pass
4,disolves in diluted aqueous sodium hydroxide solutions Pass
Identificaton a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. pass
b)The retention time of the major peak is confirm to the RS pass
Loss on Drying Not more than 4.0% 0.46%
[a]20/D C=1 in 1M HCl/EtOH 1:4 +18 ~ +22o +20.9o
Assay(HPLC) Not less than 95.0% 99.18%
Levothyroxine sodium Not more than 5.0% 0.68%
Conclusion: Up to the Standard for Export
Ethisterone CAS : 434-03-7
Norethisterone CAS:68-22-4
Ethynyl estradiol CAS:57-63-6
Ethynodiol diacetate CAS:297-76-7
Chlormadinone acetate CAS.: 302-22-7
Cyproterone acetate CAS.: 427-51-0
Megestrol acetate CAS.: 595-33-5
Estradiol CAS:50-28-2
17alpha-Oestradiol CAS: 57-91-0
Estradiol Cypionate CAS:313-06-4
Estradiol enantate CAS: 4956-37-0
Estradiol valerate CAS: 979-32-8
Estradiol Benzoatae CAS:50-50-0
Estrone CAS: 53-16-7
Estriol CAS: 50-27-1
19-Norethindrone acetate CAS:51-98-9
Norethisterone enanthate CAS:3836-23-5
Testolactone CAS:968-93-4
Eplerenone CAS: 107724-20-9
Progesterone CAS:57-83-0
Medroxyprogesterone Acetate CAS: 71-58-9
- L-liothyronine