Hubei Yuancheng Saichuang Technology Co.,Ltd.

Hubei Yuancheng Saichuang Technology Co.,Ltd.

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  • City: Wuhan
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L-liothyronine

  • CAS No:6893-02-3 (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic<br />acid
    Molecular Structure

    Detailed Description

    L-liothyronine
    Synonyms:3,3’,5-triiodothyronine;3,5,3’-triiodothyronine;3’,5-triiodo-l-thyronin;4-(3-iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine;5-diiodophenyl)-3-(4-(4-hydroxy-3-iodophenoxy)-l-alanin;cytomel;l-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine;l-liothyronine
    CAS:6893-02-3
    MF:C15H12I3NO4
    MW:650.97
    EINECS:229-999-3
    mp:234-238 °C(lit.)
    alpha:23 o (c=2 in ethanol)
    storage temp.:?20°C
    form:powder
    Merck:5510
    Chemical Properties:Off-White Solid
    Usage:Thyroidic drug;Thyroid hormone.One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.

    Item Specification Result
    Appearance An odorless, almost white or buff colored powder pass
    Solubility 1,Very slightly soluble in water pass
    2,slightly soluble in alcohol pass
    3,practically insoluble in most other organic solvents pass
    4,disolves in diluted aqueous sodium hydroxide solutions Pass
    Identificaton a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. pass
    b)The retention time of the major peak is confirm to the RS pass
    Loss on Drying Not more than 4.0% 0.46%
    [a]20/D C=1 in 1M HCl/EtOH 1:4 +18 ~ +22o +20.9o
    Assay(HPLC) Not less than 95.0% 99.18%
    Levothyroxine sodium Not more than 5.0% 0.68%
    Conclusion: Up to the Standard for Export

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  • L-liothyronine
  • L-liothyronine