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Maribavir

  • CAS No:176161-24-3 1H-Benzimidazol-2-amine,5,6-dichloro-N-(1-methylethyl)-1-b-L-ribofuranosyl-
    Molecular Structure

    Detailed Description

    MaribavirMaribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97.

    IC50 value:

    Target: HCMV

    in vitro: 1263W94 inhibited viral replication in a dose-dependent manner, with a mean 50% inhibitory concentration (IC50) of 0.12 ± 0.01 μM compared to a mean IC50 for GCV of 0.53 ± 0.04 μM, as measured by a multicycle DNA hybridization assay [1].

    Target:Biochemical assay reagents

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