Clozapine (N-oxide)

• Product NameClozapine (N-oxide)
  CAS No.34233-69-7
  Purity>98%
  Min Quantity
  Price~
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  Molecular Structure

Detailed Description

Clozapine (N-oxide)Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro.

IC50 Value:

Target: 5-HT2

Clozapine N-oxide was noted to decrease 5-HT2 serotonin receptor density in rat primary cortical cells and human hippocampal SHS5Y5 neuroblastoma cells.

in vitro: Clozapine and N-desmethylclozapine antagonized 5-HT-stimulated phosphoinositide hydrolysis with IC50 values of 110 and 29.4 nM, respectively.

Target:AMPK

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