Dinaciclib

• Product NameDinaciclib
  CAS No.779353-01-4
  Purity>98%
  Min Quantity
  Price~
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Detailed Description

DinaciclibDinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.

IC50 Value: 1 nM (CDK2); 1 nM(CDK5); 3 nM(CDK1); 4 nM(CDK9)

Target: CDK2/5/1/9

in vitro: Dinaciclib is a potent DNA replication inhibitor that blocks thymidine (dThd) DNA incorporation in A2780 cells with IC50 of 4 nM.

Target:Aurora Kinase

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